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Published: Assessing Cardiorespiratory Fitness in Clinical Rehabilitation Validity of Field Exercise Tests and Patient-Reported Questionnaires

  • Publication status: Submitted
  • Type of study: Validation
  • Journal: To be determined
  • Meijer, R. ORCID iD

    Schep, G. ORCID iD

    Regis, M. ORCID iD

    Jager de, Fm. ORCID iD

    Weemaes, A. ORCID iD

    Bongers, B. ORCID iD

    Pol van de - Franse, L ORCID iD

    Savelberg, H. ORCID iD

    Hooff van, M. ORCID iD

  • Affiliations: Maastricht University, Maastricht University Medical Center, Máxima Medical Centre, The Netherlands Cancer Institute, Tilburg University
  • Population: Oncology, Cardiac, Chronic Heart Failure
  • DOI: https://doi.org/10.1097/phm.0000000000003053
  • PMID: 42296456
Objectives

To evaluate criterion and construct validity of field exercise tests and patient-reported questionnaires compared with cardiopulmonary exercise testing (CPET) to estimate cardiorespiratory fitness (CRF) in clinical rehabilitation.

Design:

Participants were included at the start of a cardiopulmonary or oncologic rehabilitation program. All patients performed a CPET, steep ramp test (SRT), and 6-minute walk test (6-MWT) and completed the Duke activity status index (DASI), veterans-specific activity questionnaire (VSAQ), and FitMáx© questionnaire (FitMáx). Work rate at peak exercise at the SRT (SRT-WRpeak), distance walked at the 6-MWT (6-MWD), and oxygen uptake at peak exercise (VO2peak) estimated by the questionnaires were compared with measured VO2peak during CPET.

Results:

Sixty-nine patients (57% female) were included, with a median (IQR) age of 58 (46-66) years. Correlations of SRT-WRpeak and 6-MWD with CPET-VO2peak were ρ=0.87 (95%-CI 0.78-0.92) and ρ=0.40 (95%-CI 0.17-0.58), respectively. Correlations of DASI-VO2peak, VSAQ-VO2peak, and FitMáx-VO2peak with CPET-VO2peak were ρ=0.37 (95%-CI 0.13-0.56), ρ=0.51 (95%-CI 0.30-0.68), and ρ=0.78 (95%-CI 0.65-0.87), respectively.

Conclusions:

SRT-WRpeak and FitMáx-VO2peak strongly correlated with CPET-VO2peak, whereas the 6-MWD, DASI-VO2peak and VSAQ-VO2peak showed a moderate correlation. Consequently, the SRT and FitMáx are considered the best alternative exercise test and questionnaire to estimate CRF when CPET is not feasible.